Flights from Medellín to Santiago

MDESCL

Jose Maria Córdova International Airport (Medellín, Colombia) → Comodoro Arturo Merino Benítez International Airport (Santiago, Chile)

Also known as Medellín, Santiago.

Est. nonstop
~5h 54m
Distance
4,426 km
One-way from
$232
Airlines
JetSMART

Fares by month

One-way, per person

Lowest fares Aviasales travelers found in recent searches; some may include a connection. Prices change often — tap a month to see live fares.

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Medellín to Santiago — frequently asked

How long is the flight from Medellín to Santiago?
MDE–SCL is about 5h 54m nonstop, covering 4,426 km (2,750 mi).
Which airlines fly nonstop from Medellín to Santiago?
JetSMART operates this route nonstop.
How much is a flight from Medellín to Santiago?
One-way fares on MDE–SCL recently started from $232. The lowest recent fare is for travel in December 2026. Fares change daily, so check current prices before booking.